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Introduction to protein classification at the EBI

Pfam

InterPro

ExPASy

PDB sequence motif

Lecture notesEdit

Describing and classifying proteins All beta sheet, all alpha helix, mixed alpha-beta

1MBN Myoglobin

1C3W Bacteriorhodopsin

1GFL Green fluorescent protein, almost all beta sheet

2BNH Porcine ribonuclease inhibitor (mixed alpha beta) (UniProt)

DOMAINS

  • DNA pol I and Klenow fragment

MOTIFS

  • Leucine-rich repeat
  • Zinc finger
  • Polyhistidine tag
  • Kringle
  • Helix-turn-helix
  • Beta barrel
  • Catalytic triad of serine proteases

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